1-(2-chloroethyl)pyrrolidine Hydrochloride Basic Information, Physicochemical Properties, etc.
| Basic Information |
| Name |
1-(2-chloroethyl)pyrrolidine Hydrochloride |
| Synonyms |
1-(2-chloroethyl)-pyrrolidinhydrochloride; 1-(2-CHLOROETHYL)PYRROLIDINEHCL; 2-PYRROLIDINOETHYLCHLORIDEHYDROCHLORIDE; 2-CHLOROETHYLPYRROLIDINEHYChemicalbookDROCHLORIDE; 2-CHLOROETHYLPYRROLIDINEHCL; 2-(N-Pyrrolidino)ethylchloridehydrochloride; N-(2-Chloroethyl)pyrrolidineHCl; N-Chloroethylpyrprolidine |
| CAS Number |
7250-67-1 |
| Molecular Formula |
C6H13Cl2N |
| Molecular Weight |
170.08 |
| EINECS Number |
230-660-7 |
| Structural Formula |
 |
| Physicochemical Properties |
| Melting Point |
167-170 °C(lit.) |
| Boiling Point |
237°C(lit.) |
| Density |
0.4[at 20℃] |
| Vapor Pressure |
1.64hPa at 25℃ |
| Solubility |
Soluble in chloroform (a little), water (a little) |
| Water Solubility |
Soluble |
| Form |
Crystalline powder or crystals |
| Color |
White to almost white |
| Sensitivity |
Hygroscopic |
| Acidity Coefficient (pKa) |
/ |
| Safety and Regulatory Information |
| Merck |
|
| BRN |
3677061 |
| NIST Chemical Substance Information |
/ |
| EPA Chemical Substance Information |
/ |
| Other Information |
| Detection Methods |
Titration,NMR |
1-(2-chloroethyl)pyrrolidine Hydrochloride Application, Use, Usage, Synthesis Method, etc.
- As a pharmaceutical intermediate.
- N-(2-chloroethyl)pyrrolidine hydrochloride is a haloalkyl-substituted pyrrolidine used to prepare various pharmaceutical compounds.
- For example, the estrogen receptor antagonist nafoxidine and its analogs.
- Preparation of palbociclib hydrochloride, a highly selective cdk4/6 inhibitor, which exhibits broad-spectrum anticancer activity in a variety of human tumor xenografts.
- Preparation of 1-[2-(4-bromophenoxy)ethyl]pyrrolidine, a drug intermediate for the treatment of osteoporosis in postmenopausal women.
1-(2-chloroethyl)pyrrolidine Hydrochloride Packaging, Storage, Delivery, Transportation, etc.
Packing: 25kg/drum or Customer specified packaging
Storage: Stored in a cool dry ventilated warehouse
Delivery: delivery within 3- 5 working days
Transportation: According to your needs
FAQ About 1-(2-chloroethyl)pyrrolidine Hydrochloride
Where can I buy N-(2-Chloroethyl)pyrrolidine hydrochloride and what is the minimum order quantity?
Answer:
You can purchase it through regular chemical suppliers (such as Sigma-Aldrich, TCI, and ORIENTRED).
Different suppliers have different requirements. Usually, the minimum for laboratory grade is 100 grams, and the industrial grade may require more than 1 kilogram.
ORIENTRED does not limit the order quantity.
Does transportation require special conditions?
Answer: No, it needs to be sealed and transported at room temperature to avoid moisture and high temperature.
Is it a regulated chemical?
Answer: It is not strictly regulated internationally at present, but it must comply with local chemical management regulations.
