1-Bromo-3-methoxypropane Basic Information, Physicochemical Properties, etc.
| Basic Information |
| Name |
1-Bromo-3-methoxypropane |
| Synonyms |
3-METHOXYPROPYLBROMIDE; 1-BROMO-3-METHOXYPROPANE; 1-BROMO-3-METHOXYPROPANE 99%; 3-BROMO-1-METHOXYPROPANE; 3-Bromopropyl methyl ether; 1-Bromo-3-methoxypropane ,98%; 1-broMo-3-Methoxyproane; 1-BroMo-3-Methoxypro |
| CAS Number |
36865-41-5 |
| Molecular Formula |
C4H9BrO |
| Molecular Weight |
153.02 |
| EINECS Number |
|
| Structural Formula |
 |
| Physicochemical Properties |
| Melting Point |
|
| Boiling Point |
132°C |
| Density |
1.36 g/cm3 |
| Refractive Index |
1.4450-1.4490 |
| Solubility |
|
| Vapor Pressure |
6.6 hPa ( 20 °C)
|
| Form |
Transparent liquid |
| Color |
Colorless to light yellow |
| Stability |
|
| pH |
6-7 (H2O)
|
| Safety and Regulatory Information |
| Merck |
|
| BRN |
|
| NIST Chemical Substance Information |
1-Bromo-3-methoxypropane | CAS: 36865-41-5 |
| EPA Chemical Substance Information |
|
| Other Information |
| Detection Methods |
GC, NMR
|
1-Bromo-3-methoxypropane Application, Use, Usage, Synthesis Method, etc.
- As a commonly used alkylating agent
- Used in pharmaceutical chemistry, organic synthesis intermediates, and reagents
- Pharmaceutical chemistry is used to synthesize the drug molecule Brinzolamide, which is used to treat ocular hypertension and open-angle glaucoma.
- In organic synthesis, the bromine unit is mainly used as an alkylating agent to protect oxygen atoms or nitrogen atoms due to its easy leaving property.
- Used to synthesize a variety of functional compounds, such as esters, ethers, alcohols, etc.
- Used as a precursor for surfactants, dyes, and fragrances.
Preparation method
- Add 40g (0.2mol) of 1,3-dibromopropane to 50ml of methanol and add sodium methoxide (methanol solution).
- Reflux for 6 hours, add 100ml of water and stir.
- Extract with n-pentane and dry with anhydrous sodium sulfate.
- After filtration, evaporate the n-pentane solvent to obtain 30g of crude 1-methoxy-3-bromopropane as a colorless oil.
1-Bromo-3-methoxypropane Packaging, Storage, Delivery, Transportation, etc.
Packing: 25kg/drum or Customer specified packaging
Storage: Keep in a dark place, sealed in dry, at Room Temperature
Delivery: delivery within 3- 5 working days
Transportation: According to your needs
FAQ About 1-Bromo-3-methoxypropane
Where can I buy 1-Bromo-3-methoxypropane? What is the price and minimum order quantity?
Answer:
Purchase through chemical suppliers (such as Sigma-Aldrich, TCI, ORIENTRED), and the minimum order quantity for laboratory grade is usually 100 grams.
Please feel free to contact us for the latest quote.
What should I pay attention to when handling?
Answer:
- 1-Bromo-3-methoxypropane is irritating and corrosive.
- When using it, you should pay attention to protective measures, such as wearing gloves, goggles and protective clothing.
- Avoid inhaling its vapor and avoid contact with skin and eyes.
- Avoid open flames and static electricity during storage and handling.
- Comply with relevant environmental regulations when disposing of waste.
- In case of inhalation or contact, seek medical attention immediately.
Can the cost be reduced?
Purchasing 1-Bromo-3-methoxypropane in bulk from ORIENTRED can get lower costs.
