1-(2,6-dichlorophenyl)-2-indolinone Basic Information, Physicochemical Properties, etc.
| Basic Information |
| Name |
1-(2,6-dichlorophenyl)-2-indolinone |
| Synonyms |
DiclofenacPotassiumⅠ:1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one;DiclofenacSodiumImpurityⅠ:1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one;Indolinone(DiclofenacAmide,DiclofenacLactam);DICLOFENACRELATEDCOMPOUNDA(50MG)(N-(2,6-DICHLOROPHENYL)INDOLIN-2-ONE);1-(2,6-Dichlorophenyl)-2,3-dihydro-1H-indole-2-one;DiclofenacAmide;6-Dichlorophenyl)-2-indolinone;N-(2,6-Dichlorophenyl)-Indolin-(2)-One |
| CAS Number |
15362-40-0 |
| Molecular Formula |
C14H9Cl2NO |
| Molecular Weight |
278.13 |
| EINECS Number |
239-399-3 |
| Structural Formula |
 |
| Physicochemical Properties |
| Melting Point |
115-119°C |
| Boiling Point |
488.6±45.0 °C(Predicted) |
| Density |
1.432±0.06 g/cm3(Predicted) |
| Refractive Index |
/ |
| Solubility |
Soluble in chloroform (a little), methanol (a little) |
| Water Solubility |
/ |
| Form |
Crystalline solid |
| Color |
Dusty grey or brown red |
| Stability |
Stability |
| Acidity Coefficient (pKa) |
-4.85±0.20(Predicted) |
| Safety and Regulatory Information |
| Merck |
/ |
| BRN |
1538309 |
| NIST Chemical Substance Information |
/ |
| EPA Chemical Substance Information |
/ |
| Other Information |
| Detection Methods |
/ |
1-(2,6-dichlorophenyl)-2-indolinone Application, Use, Usage, Synthesis Method, etc.
- Mainly used as a diclofenac intermediate
The chemical name of diclofenac sodium is 2-(2,6-dichlorophenylamino)phenylacetic acid sodium. It is mainly used as an antipyretic and analgesic, non-steroidal anti-inflammatory drug, and is often used in the treatment of various mild to moderate acute and chronic pain in orthopedics.
Such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc.
1-(2,6-Dichlorophenyl)indolin-2-one is hydrolyzed with inorganic alkali to obtain the target product diclofenac sodium
Synthesis Method
In the presence of a phase transfer catalyst, N-phenyl-N-(2,6-dichlorophenyl) chloroacetamide and Lewis acid are subjected to a Friedel-Crafts reaction to prepare the intermediate of diclofenac sodium 1-(2,6-Dichlorophenyl)oxindole.
1-(2,6-dichlorophenyl)-2-indolinone Packaging, Storage, Delivery, Transportation, etc.
Packing: 25kg/drum or Customer specified packaging
Storage: Sealed in a dry, Room Temperature
Delivery: delivery within 3- 5 working days
Transportation: According to your needs
FAQ About 1-(2,6-dichlorophenyl)-2-indolinone
Where can I buy 1-(2,6-Dichlorophenyl)indolin-2-one? Is it expensive?
Answer:
You need to purchase it through a professional chemical supplier or custom synthesis company, such as ORIENTRED.
Its price is changing all the time, please contact us for the latest price.
What is 1-(2,6-Dichlorophenyl)oxindole used for?
Answer: Mainly used as a diclofenac intermediate
Can the waste be dumped directly?
Answer: No! It must be handed over to a qualified environmental protection company for disposal to avoid polluting the environment.
